Human Sera
Cayman Chemical 1S 3S3AmInomethylcyclope 50mg
A polyphenolic antioxidant that is abundant in many fruits vegetables plant bark and peels has anti-carcinogenic anti-mutagenic anti-inflammatory and organ-preserving properties blocks methylation of H3R17 by CARM1 without significantly altering histone acetylase or DNA methyltransferase activity
Cayman Chemical Cortol 50mg
An analytical reference standard that is structurally similar to known phytocannabinoids has been found in Cannabis intended for research and forensic applications
Cayman Chemical Pteryxn 50mg
A peptide agonist of CaSR selective for CaSR over a panel of 33 receptors and ion channels as well as the norepinephrine transporter at 10 UM increases intracellular calcium levels in HEK293T cells expressing the human CaSR receptor (EC50 0 53 UM) inhibits parathyroid secretion from primary rat parathyroid cells (EC50 0 36 UM in the presence of calcium) decreases parathyroid hormone and calcium in plasma and serum respectively in a model of chronic renal insufficiency with secondary hyperthyroidism in nephrectomized rats fed high-phosphorus diet at 0 3 1 and 3 mg/kg
Cayman Chemical BHC 50mg
A selective allosteric orally bioavailable pan-Akt inhibitor (IC50s 5.0 4.5 and 16 nM for Akt1 Akt2 and Akt3 respectively)
Cayman Chemical Cortol 100mg
An analytical reference standard that is structurally similar to known phytocannabinoids intended for research and forensic applications
Cayman Chemical Heptadecnoyl EthnolamIde 100mg
A F508del-CFTR corrector increases CFTR levels in CFBE41o- bronchial epithelial cells expressing F508del-CFTR fused to HRP (EC50 0.13 UM) and the transepithelial current in primary human bronchial epithelial cells isolated from a patient with cystic fibrosis with the F508del-CFTR mutation (EC50 0.028 UM)
Cayman Chemical Fluprostenol Lacton DIol 100mg
A G protein-biased peptide agonist of GLP-1R selectively induces cAMP accumulation in HEK293 cells expressing human GLP-1R overBarrestin recruitment in CHO-K1 cells expressing human GLP-1R (EC50s 0.63 and 79 nM respectively) induces insulin secretion in INS-1 832/3 cells (EC50 6.3 nM) reduces food intake and body weight increases plasma insulin levels and decreases plasma glucose HbA1c glucagon and triglyceride levels in diabetic db/db mice from 1.5-6 nmol/kg
Cayman Chemical Asarone 100mg
Antgen purfed eggshell protens (Zrp and small amounts of zona pellucda protens) from Atlantc salmon (S salar) Host mouse clone MN2B4 CrossReactvty ( ) Atlantc salmon (S salar) (reacts prmarly wth B monomer) ranbow trout (O mykss) and Arctc char (S alpnus) Zrp Applcaton(s) WB and ELSA sotype gG1K
Cayman Chemical Cntla astca Kampfrl 100mg
An analog of PGF2a containing a 17-phenoxy group on the lower side chain and an isopropyl ester at the C-1 position
Bio IVT HUMAN A/B SERUM 100ML MIN=2
Human AB serum derived from apharesis plasma. Steile filtered, mycoplasma and endotoxin tested
Cayman Chemical BHC 100mg
An HIV maturation inhibitor (IC90 6.4 nM) active against a variety of HIV isolates
Cayman Chemical Lndane 100mg
A DNA alkylating agent active metabolite of dacarbazine (DTIC) active degradation product of temozolomide cytotoxic to L-cells and decreases thymidine and uridine uptake by 55 and 65 respectively at 1 mM cytotoxic to TLX5 murine lymphoma cells induces formation of mammary adenofibromas in rats when administered at a cumulative dose of 890 mg per animal over 14 weeks
Cayman Chemical Ocmene 50mg
A cell-permeable benzoxazolo-sulfonamide compound that blocks human FBPase-1 enzymatic activity by competing at the AMP allosteric binding site (IC50 3 4 UM Ki 1 1 UM) blocks glucose production in starved rat hepatoma cells (IC50 6 6 UM)
Cayman Chemical Fluprostenol Lacton DIol 50mg
A building block has been used in the synthesis of drUG-linker molecules for ADCs